GOOD NEWS!1 HIV VACCINE DISCOVERED AND TRIALS BEGIN IN SOUTH AFRICA

“It gives the tick on all four, it does look promising and it should launch,” Gail Bekker said. “We wanted to see a particular immune picture that would suggest that a big efficacy trial would be likely to yield results,” she said.
“[This] was like the gatekeeper of will we or will we not go ahead,” Fauci said, “and the answer is ‘yes’.

A larger-scale trial of the vaccine will now begin in 5,400 people across four sites in South Africa in November 2016 and run for three years. A fifth dose of the vaccine will also be given in hope of longer-lasting protection.
The Thai study showed 60% protection against HIV after one year, but this fell to 31% by the end of the trial. The team hopes the new regimen will bring protection levels back up.

“We want to get it up to 60% and keep it there,” Fauci said. “That’s the reason for the boost and the reason for the adjuvant,” he said.

Experts have long been awaiting a vaccine showing enough efficacy to dent the numbers of people newly infected with HIV each year, which fell by 0.7% between 2005 and 2015, according to a study published Tuesday and presented at the conference.

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